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New Model Used To Explain How Far Brain Stimulation Goes

Parkinson’s disease is a complex chronic motor system disorder resulting from the death of dopaminergic neurons in the substantia nigra pars compacta. The cause of this cell death is unknown, but it is thought to be due to genetic and environmental factors. 

This disease results in the loss of muscle control and movement. In the meantime, if you have issues with your movement, you can contact Kinetic Rehabilitation physio Adelaide.

There is no cure for Parkinson’s disease, but there are treatments that can help manage the symptoms. One treatment option is deep brain stimulation (DBS). DBS involves the implantation of a device that delivers electrical stimulation to specific brain areas.

DBS is considered an effective treatment for Parkinson’s disease, but it is unclear how it works. A new recent study published in the journal Neuron has proposed a model explaining how DBS works.

According to the model, DBS works by reducing the activity of a specific type of Neuron called an inhibitory interneuron. These neurons are essential for controlling the activity of other neurons. Inhibitory interneurons are typically more active in patients with Parkinson’s disease.

The researchers believe that by reducing the activity of these inhibitory interneurons, DBS may help restore the balance of neuronal activity in the brain and improve symptoms. In addition, this model provides a new way of thinking about how DBS may work and could be leading to new and improved treatments for Parkinson’s disease.

“Deep brain stimulation has been used to treat Parkinson’s disease for over a decade, but its mechanisms have been largely unknown,” said senior study author Michael Long, an associate professor of neural sciences and physiology at NYU Langone Health. “Our study provides the first detailed computational model of how this therapy might work.”

Scientists at Boston University and The Picower Institute for Learning and Memory at MIT have a new study presenting a detailed computational model for howDeep Brain Stimulation (DBS) might alleviate symptoms of Parkinson’s disease by resetting imbalanced networks in the brain.

DBS is a surgical procedure involving electrodes deep into the brain to deliver electrical impulses. It is approved to treat certain movement disorders, including Parkinson’s disease, essential tremor, and dystonia. Though it effectively reduces symptoms, the mechanisms underlying its therapeutic effects are not well understood.

The new recent study, published in the journal Neuron, provides a detailed computational model for how DBS might work to alleviate symptoms of Parkinson’s disease. Learn more information here about Kinetic Rehabilitation physio Adelaide.

The model is based on the hypothesis that DBS works by reducing the activity of a specific type of Neuron called an inhibitory interneuron. These neurons are essential for controlling the activity of other neurons. Inhibitory interneurons are typically more active in patients with Parkinson’s disease. If you have been diagnosed with Parkinson’s disease or are caring for someone who has, don’t hesitate to get in touch with Kinetic Rehabilitation for more information on our services. We offer a free initial consultation to discuss your individual needs and how we can help you achieve your goals.

This still needs more research to be concrete, but the new model does provide some insight that DBS may help restore the balance of neuronal activity in the brain and improve symptoms for those with Parkinson’s disease.

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